Ginseng Research Today is a free monthly online journal that collates and summarizes the latest research about Ginseng, including details on american ginseng, panax, benefits, side effects.

Structural Characterization and DPPH Radical Scavenging Activity of an Arabinoglucogalactan from Panax notoginseng Root.

Wu Y, Wang D

yw2248@columbia.edu.

The structure of an antiradical arabinoglucogalactan ( 1) from Panax notoginseng roots was determined. This polymeric carbohydrate was obtained through successive phosphate buffer (pH 7.0) extraction after cold-water pretreatment and purification by ion-exchange and gel-filtration chromatography. Monosaccharide analysis, permethylation analysis, NaIO 4 and CrO 3 oxidations, Smith degradation, graded acid hydrolysis, and IR and NMR experiments indicated that 1 possesses a backbone of (1-->3)-linked beta- d-galactofuranosyl residues, with branches of alpha- l-Ara f-(1-->4)-beta- d-Glc p-(1--> residues at O-6. Additionally, 1 exhibited high scavenging activity against DPPH free radicals with a 50% scavenging concentration (SC 50) of 11.72 +/- 0.91 microg/mL, suggesting that this arabinoglucogalactan is a potential antiradical.

Published 25 February 2008 in J Nat Prod, 71(2): 241-5.
Full-text of this article is available online (may require subscription).

© 2004-2008 Ginseng Research Today. All Rights Reserved.