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Proteomic analysis of Korean ginseng (Panax ginseng C.A. Meyer).

Nam MH, Kim SI, Liu JR, Yang DC, Lim YP, Kwon KH, Yoo JS, Park YM

Metabolome Analysis Team, Korea Basic Science Institute, Seoul 136-701, Korea.

Although many reports have been published regarding the pharmacological effects of ginseng, little is known about the biochemical pathways operant in ginsenoside biosynthesis, or the genes involved therein. Proteomics analysis is an approach to elucidate the physiological characteristics and biosynthetic pathways of ginsenosides, main components of ginseng. In this review, we introduced the recent progress in proteomics studies of ginseng (Panax ginseng C.A. Meyer). We briefly reference the genomic analyses of P. ginseng, without which proteomics approaches would have been impossible. Functional genomics studies regarding secondary metabolism in P. ginseng are also introduced here, in order to introduce possible future prospects for further study.

Published 17 January 2005 in J Chromatogr B Analyt Technol Biomed Life Sci, 815(1): 147-55.
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